This is a prevalent condition which includes fatigue, weakness, anxiety, loss of appetite and guilt attributed to semen loss through nocturnal emissions, urine and masturbation. This culture-bound syndrome is seen in mostly young boys in there teens and twenties. The myth related to semen loss is “it takes 40 days for 40 drops of food to be converted to one drop of blood, 40 drops of blood to make one drop of bone marrow and 40 drops of bone marrow form one drop of semen” and hence semen loss is considered huge loss of health. “Dhat” word origin is from Sanskrit word dhatu, meaning “metal,” “elixir” or “constituent part of the body” which is considered to be “the most concentrated, perfect and powerful bodily substance, and its preservation guarantees health and longevity.” Boys due to Dhat syndrome can present with depression or anxiety symptoms or even as sexual dysfunction. There are enough historical evidences that similar kinds of syndromes were prevalent in Europe, USA and Australia in the 19th century, which disappeared in response to changes in social and economic factors.